Contact with eyes may cause severe irritation, and p ossible eye burns. In four human subjects exposed to methylene chloride 350 mgcu m for 2 hr, an average of 22. The recovery of analyte from the collection medium during storage must be 75% or greater. Hazardous in case of skin contact irritant, permeator. The above information is believed to be correct but does not purport to.
Trace impurities in solvents commonly used for gas. Component immediately dangerous to life health idlh methylene chloride dichloromethane 75092 2300 ppm idlh propylene oxide 75569 400 ppm idlh hazardous combustion products. Recommendations apply only to national institute for occupational safety and health niosh approved respirators. Safety data sheet methylene chloride tech version 1. Any additive, if used, in the product or process is of. Methylene chloridedichloromethane exposure can cause central nervous system, liver, and cardiovascular effects. The recovery of methylene chloride from samples used in 17day storage tests remained above 99. It is volatile, producing potentially toxic concentrations at room temperature. Metabolic conversion of methylene chloride to carbon monoxide may place persons with preexisting coronary artery disease at increased risk. Figure 5 shows a picture of the container from which talstrip ii was poured in this incident.
Methylene chloride 75 09 2 100 toxicological data on ingredients. This product contains a chemical known to the state of california to cause cancer. Methylene chloride please ensure that this msds is given to, and explained to people using this product. Synonyms include dichloromethane, methylene bichloride, methane dichloride, and methylenedichloride. The information contained in this sds does not constitute a risk assessment, and should not replace the users own assessment of risks as required by other health and safety legislation.
Methylene chloride is a solvent found in paint and varnish strippers that are used to remove paint or varnish coatings from a variety of surfaces. Dichloromethane is also known as methylene chloride and dcm. A common synonym for methylene chloride is dichloromethane. Mdhs70 general methods for sampling airborne gases and vapours. Mec prime mec prime is special high purity grade of methylene chloride for use in pharmaceutical drug tablet and film coating, antibiotics, vitamins, pharma carbomers mec prime worlds sole owner of mecprime, perkloneand triklone banner chemicals uk flying the flag of excellence for over 160 years queens award winner. Page 2 of 5 safety data sheet methylene chloride take off contaminated clothing and wash before reuse. A unit of srm 3008 consists of two 5 ml sealed borosilicate glass ampoules of a gravimetrically prepared solution of methylene chloride in methanol. Hazardous to health regulations coshh 2002 as amended. Skin contact wash off immediately with plenty of water for at least 15 minutes. Methylene chloride is metabolically converted to carbon monoxide after systemic absorption, which yields increased concentrations of carboxyhemoglobin in the blood. Do not store together with reducing agents, heavymetal compounds, acids and alkalis. Dichloromethane contains 40150 ppm amylene as stabilizer, acs reagent. Hazards identification potential acute health effects.
July 3, 2007 the dow chemical company page 4 of 7 epidemiological studies on more than 6,000 people exposed to methylene chloride in their workplace using over 35 years of observations showed no. Preliminary information on manufacturing, processing. This colorless, volatile liquid with a moderately sweet aroma is widely used as a solvent. Vaporphase methylene blue is degraded in the atmosphere by reaction with photochemically produced hydroxyl radicals with an estimated halflife of about 1.
It is a very volatile liquid that penetrates readily through standard nitrile laboratory gloves. Methylene chloride, methylene chloride cas number 75092. Anhydrous methyl chloride water content less than a dew point of 40of 40oc can be handled in carbon or stainless steel, c opper and bronze. Dichloromethane material safety data sheet cas no 75092. Most spills of methylene chloride dichloromethane outside of a chemical fume hood should be referred to the oeso spill response team by calling 911 from a campus phone or 9196842444 from any phone. Section 2 hazards identification statement of hazardous nature this product is classified as.
It is metabolized by the body to carbon monoxide, and can affect the bloods ability to transport oxygen. Methylene chloride ch2cl2 analytical methylene chloride. Hydrogen chloride, chlorine, phosgene, oxides of carbon sensitivity to mechanical impact. Locating and estimating sources of methylene chloride. Oshas methylene chloride standard industries covered the osha methylene chloride standard title 29 code of federal regulations, parts 1910. Reaction of hydrogen chloride and methanol result in methyl chloride. Material safety data sheet msds methylene chloride. Product stewardship summary methylene chloride summary methylene chloride is a colorless, volatile liquid. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. Phe publications gateway number 2014790 pdf, 271kb. Methylene chloride is produced using methyl chloride and chlorine.
In seven subjects exposed to 710 mgcu m for 2 hr, the corresponding value was 81. Methylene chloride uses, benefits, and chemical safety facts. Product identification name methylene chloride synonyms dichloromethane. Methylene chloride revision date 28nov2019 eye contact rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. If unconscious place in recovery position and seek medical advice. Iarc lists methylene chloride in group 2b sufficient evidence in animals, insufficient evidence in humans. July 3, 2007 the dow chemical company page 4 of 7 epidemiological studies on more than 6,000 people exposed to methylene chloride in their workplace using over 35 years of observations showed no increase in deaths from cancer or any other disease. Very hazardous in case of eye contact irritant, of ingestion, of inhalation.
Dichloromethane dcm or methylene chloride is an organochloride compound with the formula c h 2 cl 2. Methylene chloride is a solvent found in paint and varnish strippers that are used to remove paint or varnish. To achieve the best quality of methylene chloride, trace amounts of impurity must be detected and removed from this solvent. Figure 5 shows a picture of the container from which tal. Ntp lists methylene chloride as a potential carcinogen. Methylene chloride, also known as dichloromethane and methylene dichloride, is a clear, colorless liquid with a slightly sweet scent that is primarily used as an industrial solvent and also as a potent paint stripper and paint thinner. The niosh recommended exposure limit rel for methylene chloride has not been established. Safety data sheet methylene chloride page 5 issued. Employees in the area should be prepared to clean up minor spills, including most spills confined to the chemical fume hood. Methylene chloride also known as dichloromethane is a volatile, colorless liquid with a sweet, chloroformlike odor.
Detection of trace constituents in a solvent can be performed by concentrating a. It is slightly soluble in water and miscible with most organic solvents. Methylene chloride is widely used as an extraction solvent in pharmaceutical, environmental, food and chemical industries. July, 2010 and is valid for 5 years from this date. Methylene chloride is removed from the body mainly in expired air and urine. Detecting trace amounts of impurity in methylene chloride. Excess methyl chloride then reacts with added chlorine to produce methylene chloride, chloroform, and carbon tetrachloride as coproducts. The effects of acute exposure to methylene chloride dichloromethane are due to its cns depressant properties, which have resulted in fatalities. At low temperature and high pressure, the reaction is more selective to methylene chloride. A dense, nonflammible colourless liquid at room temperature b. Move the affected person from the hazardous exposure immediately. Dichloromethane is a member of the class of chloromethanes that is methane in which two of the hydrogens have been replaced by chlorine. This material is considered hazardous by the osha hazard communication.
Material safety data sheet page 1 of 2 methylene chloride. Oct 21, 2014 at room temperature, methylene chloride is a clear, colorless liquid with a pleasant odor. Parsons department of chemistry, arizona state university, tempe, az 85281 u. Sep 26, 2019 toxicological profile for methylene chloride. When heated to decomposition, emits acrid fumes of hydrogen chloride and phosgene. Valve protection caps must remain in place unless container is. When handling dichloromethane in the workplace, use the following safety precautions. Although it is not miscible with water, it is polar, and miscible with many organic solvents. Methylene chloride has produced lung and liver tumors in mice and mammary tumors in female rats in a two year inhalation study. It is a solvent and is used many applications including paint removers. Under normal conditions it has no flash point and can be.
Environmental protection agency epa issued a final rule banning the use of methylene chloride in all paint removers for consumer use, effective november 24, 2019. First aid measures remove victim to fresh air and keep at rest in a position comfortable for breathing. Refer to the niosh pocket guide to chemical hazards for more information. If released to the atmosphere, methylene blue will exist as both vapor and particulate in the ambient atmosphere. Osha method 80 is an example of a validated method of sampling and analysis of mc. Methylene chloride is an aggressive solvent, making it a good choice for paint removers as well as an effective carrier and extraction solvent.
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